Integra

Introduction
Marathon running is growing in popularity, and many diabetic patients are participating in various marathon races all
over the world each year. This study aimed to investigate the prevalence and extent of glycemic excursions (hypo- and
hyperglycemic) during a long distance run in patients with well-controlled diabetes mellitus using a continuous glucose
monitoring system (CGMS).

Methods
Five subjects with type 1 and one patient with type 2 diabetes mellitus were monitored with Medtronic MiniMed
CGMS during the 2002 Vienna City Marathon (patient 1-3) or the "Fernwärme run" (patient 4-6) a long distance run of
15. 8 km.

Results
All six patients finished race. The CGSM system was well tolerated in all patients over an average duration of 34± 4.0
hours and it did not limit the patient’s activities. The mean running time for the marathon was 257±8 minutes (247 to
274 minutes) and for the Fernwärme run 134±118 minutes (113 to 150 minutes). A total of 1470 blood glucose
measurements (mean 245 readings per subject) were performed. During and after race frequent hypo- and
hyperglycaemic episodes with and without clinical symptoms were measured.

Conclusions
Our data confirm that the CGMS may help to identify asymptomatic hypoglycaemia or hyperglycaemia during and after
a long distance run. The system also may be helpful in learning about the individual changes of glucose during and after
race and may protect hypoglycaemic or hyperglycaemic periods in furthers races.

References
[1]. Bode BW. et al. (1999). Diabetes Res Clin Pract 46:183-190.
[2]. Bode BW. et al. (2000). Diabetes Technol Ther 2(Suppl.):S43-S48.
[3]. Desouza C. et al. (2003). Diabetes Care 26(5):1485-9.
[4]. Grimm J. et al. (1993). Diabetes Care 16:1624.
[5]. Hay LC. et al. (2003). Diabetes Technol Ther 5(1):19-26.
[6]. Mastrototaro J. (1999). J Pediatr Endocrinol Metab 12:751-758.
[7]. Meinders AE. et al. (1988). Diabetes Care 11:1-7.

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