ácido Ursólico Pode Ser Eficaz na Redução da Adiposidade e Aumento da Massa Muscular? Uma Revisão

Objetivo: Revisar estudos que avaliaram o uso do AU em seres humanos e seus efeitos na adiposidade e massa muscular. Métodos: A busca dos artigos foi realizada na base de dados PubMed. Foram excluídos estudos irrelevantes ao tema e experimentos com animais, sendo incluídos na revisão quatro trabalhos. Resultados e Discussão: Os estudos apontam que o AU está associado com redução da gordura corporal (via termogênese) e controle glicêmico, e que, associado ao exercício resistido pode aumentar a síntese proteica (via a sinalização da mTOR). Conclusão:  São necessários mais estudos clínicos para esclarecer a dose terapêutica, o público alvo e o efeito na perda de gordura corporal e/ou ganho de massa muscular.

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