Disorders of gut-brain axis: A review highlighting the treatments so far.

There is a high prevalence of disorders of gut-brain axis (DGBI) globally as well as in India. Although DGBIs have a complex pathophysiology, they are a result of an interplay between physiological, environmental, psychological and genetical factors of a person. Three of the most researched DGBIs are irritable bowel syndrome (IBS), functional dyspepsia (FD) and functional constipation. Current researches point out visceral hypersensitivity, altered gastro-intestinal motility, intestinal inflammation, triggered immune activation, and increase in intestinal permeability and gut dysbiosis as the main mechanisms involved. A high number of individuals presenting in clinical setting with exacerbating symptoms have reported to find relief from medication. However, evidence from researches have suggested the use of complementary or alternative therapies along with medicines for a better result. This review explores all the potential complementary or alternative therapy treatments used for DGBI to achieve symptom relief and a better quality of life.

Acessar