Mood States And Cytokine Correlation In Female Soccer Players With And Without Premenstrual Syndrome (pms)
Por Roberta Foster (Autor), Mauro Vaisberg (Autor), Juliana de Melo Batista dos Santos (Autor), Luiz Antonio Luna Junior (Autor), André Luis Lacerda Bachi (Autor), Rodolfo de Paula Vieira (Autor), Catherine Machado Katekaru (Autor), Lucas Guimarães Pagani (Autor), Matheus Cavalcante de Sá (Autor), Zsuzsanna Ilona Katal (Autor).
Em 40º Simpósio Internacional de Ciências do Esporte SIMPOCE
Resumo
Introduction: PMS is defined as a group of physical and behavioral changes beginning in the luteal phase and ending during menstruation1. It’s known that intense physical activity is closely associated with changes in many aspects of immune response, such as cytokine production2. In addition it is relevant that cytokines act on behavior and mood states3-5, and may adversely affect the behavioral performance. The aim of this study was to evaluate mood states and its relation with cytokine production in female soccer players with (PMS) and without PMS (nPMS) in 4 moments: before and after the game and in the two phases of the menstrual cycle: follicular and luteal. Methods: Fifty-two eumenorreic soccer players were evaluated (age:19.8 ± 4.7 years). The PMS and phases of the menstrual cycle were determined by monitoring for 3 consecutive months. Evaluation of cytokines IL-1β, IL-6, IL-8, IL-10 and TNF-α were performed in urine and quantified by Flow cytometry method. The renal function was verified through creatinine analysis. Mood states were evaluated through the Brunel mood scale. This study was approved by the Ethics Committee in Research, from UNIFESP (No.1604/10). ANOVA and Spearman correlation with significance level of 5% were used for data analysis. Results: No statistical significant correlations were found between mood states and cytokines IL-1β, IL-6, IL-8 and TNF-α. The results of correlation between mood states and the cytokines IL-10 are showed in table 1. No difference in renal function was found in both groups and in the 4 evaluated moments. Discussion: The correlations observed in the group nPMS show that IL-10 can influence the mood states in athletes corroborating other studies3. Conclusion: The results observed in this study show that the anti-inflammatory cytokine is correlated with the emotion considered positive in the nPMS athletes, reinforcing the suggestion that the expression of different emotions in the context of the sport environment is influenced by neuro-immuno-endocrine mechanism.
