The purpose of this study was to reveal whether change of direction and small-sided game practises are distinctive factors in regional amateur football players. 36 male football players volunteered in the study: this consisted of Small-sided Game Group (SSG) (n:12, age: 24.41±3.65 years, height: 178.33±4.87cm, weight: 76.07±5.15kg, body fat: 13.42±2.90 percent, BMI: 23.24±2.38kg/m2), Change of Direction Group (CoDG) (n: 12, age: 25.25±1.76 years, height: 176.9±5.52cm, weight: 76.02±4.02kg, body fat: 11.31±2.88 percent, BMI: 22.50±2.16kg/m2), and Control Group (CTRLG) (n: 12, age: 23.67±3.94 years, height: 178.92±4.52cm, weight: 76.71±3.67kg, body fat: 14.10±3.30 percent, BMI: 23.45±1.46kg/m2). At the beginning and end of a 10-week period, body composition, sprint speed, vertical jump, reactive agility, 10-8-8-10m change of direction, and zig-zag agility tests were conducted with the athletes. The data were analysed via SPSS 23.0 (SPSS Inc., Chicago, IL, USA). Shapiro-Wilk test was used to determine the normality of the data, and variation homogeneity was tested using Levene’s Test of Homogeneity of Variance. The analysis of the data was done using Ancova Test, and the significance value was found as p<0.05. When the values of the groups were compared, it was found out that SSG and CoDG showed more meaningful results than CTRLG across all the parameters (p<0.05). It was concluded that compared to routine football training, small-sided game and change of direction training had distinctive effects on the 10m, 15m, 30m sprint speed, vertical jump, 10-8-8-10m change of direction, zig-zag agility, and reactive agility parameters. Coaches can be suggested they plan the training schedules taking these factors into consideration.