Neurodynamic mobilization in painful diabetic peripheral neuropathy: A narrative review

Painful diabetic peripheral neuropathy is characterized by chronic pains and altered mechano- sensitivity that affects activities of daily living, impairs sleep, restricts mobility, and causes anxiety, depression and reduced social participation. Despite its high prevalence and substantial health impact, it still goes undiagnosed and untreated. Methods: Clinical treatment of PDPN is difficult, dissatisfactory, and associated with various side effects. The role of physiotherapy seems promising in PDPN. Results: Various research has been done on the role of different physiotherapeutic modalities and exercises in the alleviation of pain and other sensory parameters in patients with PDPN. Neurodynamic mobilization (NDM) reduces neural edema and results in remyelination of affected peripheral nerves. Though its role in neuropathic pains in various conditions, including diabetes, is established, similar studies are available that have explored its effects in animal and cadaver models in PDPN. Still, there is a dearth of studies proving its effectiveness in human models. Conclusion: This review outlined the justification for more prospective research to gauge the effectiveness of NDM in reducing pain and other sensory problems in the PDPN

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