Dopagem na Atividade Física e Esportes

Doping tests for methandienone, stanozolol and dehydrochloromethyltestosterone vastly improved

Competitive athletes who still use anabolic steroids are more likely to be picked up for their use than they might imagine. Doping tests have improved dramatically in recent years, write doping hunters at the German Sport University Cologne in the British Journal of Sports Medicine. As a result, athletes who have used methandienone, stanozolol or dehydrochloromethyltestosterone show up positive for longer than the lists circulating on the web suggest.

If you have used anabolic steroids, have stopped taking them and waited long enough, then doping hunters will not be able to detect a trace in your urine. Just how long 'long enough' is you can find in a couple of minutes of googling. There are loads of online boards that post endless facts and figures.

Methandienone

Until recently for example the oral anabolic steroid methandienone [Dianabol] was a relatively safe bet for athletes. Methandienone breaks down quite fast in the body, so after a few days it didn't show up in tests.Didn't, we have to say – because that's no longer the case.

Since 2006, doping hunters have routinely looked for 18-nor-17beta-hydroxymethyl-17alpha-methyl-androst-1,4,13-trien-3-one [structural formula shown below right] in the samples they've taken. This is a methandienone metabolite [below left] which stays in the body for quite a long time. And indeed – the number of athletes that have shown up as using methandienone according to the tests has increased by a factor 4 since 2006.

Stanozolol

Another example: stanozolol [below left]. While stanozolol disappears fairly fast out of the body, this is not the case for its metabolite 17-epistanozolol-N-glucuronide [below right]. Since 2013 doping hunters have been able to detect stanozolol metabolites such as 17-epistanozolol-N-glucuronide in urine samples, and the result of this is shown in the graph below. The number of stanozolol positives has increased tenfold.

Dehydrochloromethyltestosterone

The same happened in 2013 when doping hunters examined samples in search of 4-chloro-17-hydroxymethyl-17-methyl-18-nor-5beta-androst-1,13-diene-3-ol [M3 in the figure below] and 4-chloro-17-hydroxymethyl-17-methyl-18-nor-5beta-androst-13-ene-3-ol [M4], both metabolites of dehydrochloromethyltestosterone [Oral-Turinabol] [DHCMT in the figure]. The number of athletes that doping hunters caught using this anabolic steroid rose spectacularly.

Designer steroids

For athletes who try to get round this by taking unknown anabolic steroids the authors have warning: doping hunters also find 'designer steroids' regularly. "From 2002 until 2008 a total of 22 steroidal compounds, arguably modified to remain undetected in doping controls, were identified by WADA-accredited laboratories."

Source: 
Br J Sports Med. 2014 May;48(10):820-6.

More: 
Weird doping samples 08.02.2012
Doping test confuses sulbutiamine with boldenone 18.11.2010
So that's why doping hunters don't find EPO any more 14.09.2010
Six weeks of testosterone-enanthate: more weight on the bench, faster sprint, often not detectable 12.05.2009
'Right' gene lets you inject testosterone without getting caught by doping test25.04.2009

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