O Centro Esportivo Virtual, em parceria com Institut für Angewandte Trainingswissenschaft, informa a publicaçao do presente artigo :

  1. Green, G., Aguilera, R., Ahrens, B., Starcevic, B., Kurtzman, F., Su, J. & Catlin, D. (2009). The influence of diet on isotope ratio mass spectrometry values (Der Einfluss der Ernährung auf die Werte für das Isotopenverhältnis bei der Massenspektrometrie). Clin. J. Sport Med., 19 (4), 287-292. Zugriff am 09.09.2009 unter http://dx.doi.org/10.1097/JSM.0b013e3181aad6eb

    Objectives: Athletes have increasingly used testosterone (T) and other endogenous anabolic steroids that cannot be detected by conventional gas chromatography-mass spectrometry. This led to gas chromatography-combustion-isotope ratio mass spectrometry (GC/C/IRMS), which measures the relative amount of 13C in urinary steroids. Because exogenous testosterone is relatively low in 13C content, this study will determine if consuming a diet low in 13C plants, such as soy, can be confused with a GC/C/IRMS-positive test for exogenous testosterone.Design: Cross-sectional study in which 22 vegetarians known to consume a diet depleted of 13C isotope were compared with a geographic control group of 14 subjects consuming a normal diet.Setting: Two distinct subject populations with respect to diet.Subjects: Subjects were recruited from a soy-based cooperative and control volunteers. Twenty-two of 24 research subjects completed the protocol compared with 14 of 22 control subjects.Interventions: Independent variables were [delta]13C IRMS values, urinary steroid profile, and isoflavone analysis.Main Outcome Measures: Comparisons were made with respect to dietary analysis, isoflavones, and urinary steroid measurements using GC-C-IRMS.Results: The [delta]13C values for 2 major metabolites of T (androsterone and etiocholanolone) were lower for the vegetarians than the controls (P = 0.005). The vegetarians excreted a median of 23 [mu]mol/d of total isoflavones compared with 2.7 [mu]mol/d for the control group (P = 0.0002).Conclusions: The carbon isotope ratios of urinary testosterone metabolites of vegetarians consuming a diet that is markedly depleted of 13C content were lower than that of control subjects, but not low enough to result in World Anti-Doping Agency criteria for a positive IRMS analysis. (Mikrofiche-Nummer: 17703)

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